Compare

Benchmarked on the axes the guidelines say drive choice — tolerability first. Every cell cited.

DimensionLB-102QuetiapineZiprasidonePimavanserinClozapineValaciclovir
US status
InvestigationalApprovedApprovedApprovedApprovedInvestigational
Modality
small moleculesmall moleculesmall moleculesmall moleculesmall moleculesmall molecule
FDA class
Atypical Antipsychotic [EPC]Atypical Antipsychotic [EPC]
Protection
2037 (issued)20392028
Label expansions
regulatory velocity
Weight Metabolic
FAERS within-drug share · lower is better
6.5%15.0%1.8%✓ best
Prolactin
FAERS within-drug share · lower is better
1.0%✓ best
Sedation
FAERS within-drug share · lower is better
5.2%5.3%3.6%2.8%✓ best

FAERS shares are spontaneous-reporting signals, not incidence rates. “Best” marks the lowest reported share on that axis among the compared set.