drug
as of 2026-07-01Varenicline
varenicline
MeSH D000068580
at a glance
small molecule
Pre-approval / investigational in the US
Developed by Centre for Addiction and Mental Health
17 trials in the graph
Synthesized from structured facts only — each point cited above.
Mechanism & identity
Modality
small molecule
Indications
Trials
17
Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness
NCT04011280Phase 4Completed
Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
NCT03495024Phase 4Recruiting
Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1
NCT03507127Phase 2Terminated
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
NCT01093365Phase 2Completed
Effects of Varenicline on Plasticity in Schizophrenia
NCT01934023Phase 2Completed
Effects of Varenicline on Smoking Lapse in Smokers With and Without Schizophrenia
NCT01850953Phase 4Completed
Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors
NCT00802919Phase 4Completed
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
NCT00621777Phase 4Completed
Study of the Effects of Mecamylamine and Varenicline in Schizophrenia
NCT00455650—Completed
Varenicline and Smoking Cessation in Schizophrenia
NCT01111149Phase 2Completed
Safety and Tolerability of Varenicline in Schizophrenia (SATOVA)
NCT00702793Phase 4Withdrawn
Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia
NCT00727103Phase 4Completed
Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia
NCT00554840Phase 2Completed
Varenicline Adjunctive Treatment in Schizophrenia
NCT00492349Phase 4Completed
A 6-Week Multicenter Trial Of Varenicline Tartrate For Cognitive Impairment In Subjects With Schizophrenia
NCT00743847Phase 2Withdrawn
Varenicline Effects In Schizophrenic Smokers
NCT00548470Phase 4Completed
Treating Schizophrenic Smokers: Effects on Craving, Cues and Withdrawal
NCT00781755Phase 4Withdrawn
KOLs & investigators
12
Robert C. Smith, MD, PhDKOL score 9
A. Eden Evins, MD, MPHKOL score 5
Alasdair M Barr, Ph.D.KOL score 5
L. Elliot Hong, M.D.KOL score 5
Tony P George, M.D.KOL score 5
James Levitt, M.D.KOL score 5
Professor Gary Donohoe, Ph.D.KOL score 5
Steven L Batki, MDKOL score 5
Stanley N Caroff, MDKOL score 2
Barbara D'Avanzo, Phil.D.KOL score 0
Facts & assertions
0 sourced
No assertions recorded for this entity.
relationships
The graph out of here
developer
trial
indication
KOL
Robert C. Smith, MD, PhD
personKOL score 9
A. Eden Evins, MD, MPH
personKOL score 5
Alasdair M Barr, Ph.D.
personKOL score 5
L. Elliot Hong, M.D.
personKOL score 5