indication

Major Depressive Disorder

Competitive landscape

as of 2026-07-01
Competitive set
8
8 approved · 0 pipeline

Projection timeline

actual past → guided future · protection walls overlaid
72 events
2020
2024
2028
2032
2036
2040
today
focal launch window
guided / estimated ↑
actual ↓
focal / guidedapprovallabel expansiontrial readoutcongressnclustered events (click to expand)guided (dashed = directional)competitor patent cliff

Competitive set

resolved drugs with trials in this indication
drugCompleted
Aripiprazole
US-approved 2002 · ABILIFY
Phase 46 trials
OwnerOtsuka Pharmaceutical Development & Commercialization, Inc.
Protection2041
drugCompleted
Brexpiprazole (Rexulti)
US-approved 2015 · Rexulti
Phase 32 trials
OwnerOtsuka Pharmaceutical Development & Commercialization, Inc.
Protection2033
drugWithdrawn
Lurasidone
US-approved 2010 · Latuda
—1 trial
OwnerSumitomo Pharmaceuticals America
Protection2031
drugRecruiting
Clozapine
US-approved 1989 · Clozaril
Phase 31 trial
OwnerShanghai Mental Health Center
Protection2028
drugRecruiting
Quetiapine
US-approved 1997 · SEROQUEL XR
Phase 31 trial
OwnerAstraZeneca
Protection—
drugUnknown
Risperidone
US-approved 1993 · RISPERDAL
Early Phase 11 trial
OwnerJanssen, L.P. - Investigator Initiated Studies Program
Protection2042
drugUnknown
Olanzapine
US-approved 1996 · ZYPREXA Intramuscular
Early Phase 11 trial
OwnerEli Lilly and Company
Protection2041
drugRecruiting
Cariprazine (Vraylar)
US-approved 2015 · Vraylar
Phase 21 trial
OwnerForest Laboratories
Protection2030

Market size

prevalence as a range, not a number