indication

Depression

Competitive landscape

as of 2026-07-01
Competitive set
15
9 approved · 6 pipeline

Projection timeline

actual past → guided future · protection walls overlaid
58 events
2020
2024
2028
2032
2036
2040
today
focal launch window
guided / estimated ↑
actual ↓
focal / guidedapprovallabel expansiontrial readoutcongressnclustered events (click to expand)guided (dashed = directional)competitor patent cliff

Competitive set

resolved drugs with trials in this indication
drugCompleted
Quetiapine
US-approved 1997 · SEROQUEL XR
Phase 44 trials
OwnerAstraZeneca
Protection—
drugCompleted
Paliperidone
US-approved 2006 · Erzofri extended-release
Phase 42 trials
OwnerJohnson & Johnson
Protection2041
drugCompleted
Olanzapine
US-approved 1996 · ZYPREXA Intramuscular
Phase 42 trials
OwnerEli Lilly and Company
Protection2041
drugCompleted
Ziprasidone
US-approved 2001 · Geodon
Phase 42 trials
OwnerPfizer's Upjohn has merged with Mylan to form Viatris Inc.
Protection—
drugCompleted
Aripiprazole
US-approved 2002 · ABILIFY
Phase 32 trials
OwnerOtsuka Pharmaceutical Development & Commercialization, Inc.
Protection2041
drugCompleted
Risperidone
US-approved 1993 · RISPERDAL
Phase 32 trials
OwnerJanssen, L.P. - Investigator Initiated Studies Program
Protection2042
drugRecruiting
Brexpiprazole (Rexulti)
US-approved 2015 · Rexulti
—1 trial
OwnerOtsuka Pharmaceutical Development & Commercialization, Inc.
Protection2033
drugTerminated
Haloperidol
US-approved 1986 · Haldol Decanoate
Phase 31 trial
OwnerJanssen, L.P. - Investigator Initiated Studies Program
Protection—
drugTerminated
Clozapine
US-approved 1989 · Clozaril
Phase 31 trial
OwnerShanghai Mental Health Center
Protection2028
drugTerminated
Fluphenazine
Pipeline · Phase 3
Phase 31 trial
OwnerHannover Medical School
Protection—
drugTerminated
Perphenazine
Pipeline · Phase 3
Phase 31 trial
OwnerJanssen, L.P. - Investigator Initiated Studies Program
Protection—
drugTerminated
Flupentixol
Pipeline · Phase 3
Phase 31 trial
OwnerTechnical University of Munich
Protection—
drugTerminated
Zuclopenthixol
Pipeline · Phase 3
Phase 31 trial
OwnerBirte Glenthoj
Protection—
drugTerminated
Sulpiride
Pipeline · Phase 3
Phase 31 trial
OwnerHannover Medical School
Protection—
drugTerminated
Amisulpride
Pipeline · Phase 3
Phase 31 trial
OwnerSanofi
Protection2038

Market size

prevalence as a range, not a number