drug

Bupropion

bupropion
MeSH D016642
as of 2026-07-01
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at a glance
small molecule
Pre-approval / investigational in the US
Developed by Brown University
9 trials in the graph
Synthesized from structured facts only — each point cited above.

Mechanism & identity

Modality
small molecule

Indications

Trials

9
Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure
NCT05603104Phase 3Recruiting
Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia
NCT06374290Phase 1Terminated
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
NCT02420015Phase 4Completed
Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia
NCT03132571Phase 2Terminated
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
NCT02736474Phase 4Completed
Pharmacovigilance in Gerontopsychiatric Patients
NCT02374567Phase 3Terminated
Contingent Incentives Plus Bupropion for Smoking in People With Schizophrenia
NCT00136760Phase 2Completed
Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
NCT00012558—Completed
Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1
NCT00124683Phase 2Completed

KOLs & investigators

9
Tony P George, M.D.KOL score 5
Professor Gary Donohoe, Ph.D.KOL score 5
Michael C Davis, M.D., Ph.D.KOL score 5
Jean M. Addington, Ph.D.KOL score 5
Cenk Tek, MDKOL score 5
Helge Frieling, Prof., MDKOL score 5
Jin Ho Yoon, PhD
Jennifer Tidey, PhD
Jiang Du, PhD

Facts & assertions

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No assertions recorded for this entity.
relationships
The graph out of here
developer
Brown University
company
trial
Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure
PHASE3
trial
Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia
PHASE1
trial
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
PHASE4
trial
Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia
PHASE2
trial
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
PHASE4
trial
indication
Schizophrenia
indication
Smoking Cessation
indication
Depression
indication
Psychosomatic Disorders
indication
KOL
Tony P George, M.D.
KOL score 5
person
Professor Gary Donohoe, Ph.D.
KOL score 5
person
Michael C Davis, M.D., Ph.D.
KOL score 5
person
Jean M. Addington, Ph.D.
KOL score 5
person