trial

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

NCTId NCT00012558

as of 2026-07-01

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at a glance

— · Completed

Enrollment 5,000

Sponsored by National Institute of Mental Health (NIMH)

Synthesized from structured facts only — each point cited above.

Design & status

Phase

—

Status

Completed

Enrollment

5,000

Study type

Interventional

Allocation

Randomized

Model

—

Masking

Double

Start

1998-09

Primary completion

—

Eligibility

ALL · 15 Years

Interventions & indications

Drugs

Lithium Valproate Bupropion Paroxetine lamotrigine Risperidone inositol tranylcypromine Cognitive Behavioral Therapy Family-Focused Therapy Interpersonal and Social Rhythms Therapy

Indications

Mania Bipolar Disorder Psychotic Disorders Bipolar Disorder Major Affective Disorder 2 Mood Disorders

Investigators

Professor Gary Donohoe, Ph.D.Principal Investigator

Michael C Davis, M.D., Ph.D.Principal Investigator

Sites

11 total

Stanford, United StatesDenver, United StatesBoston, United StatesWorcester, United StatesCleveland, United StatesTulsa, United StatesPortland, United StatesPhiladelphia, United StatesPittsburgh, United StatesHouston, United StatesSan Antonio, United States